Our mission is to define the biology of oncogenic viruses, especially Human T-Cell Leukemia Virus and Kaposi’s Sarcoma Herpes Virus in order to develop new methods of detection, prevention, and treatment.
Our current research is focused on defining epigenomic regulation of human T-cell leukemia virus type 1 (HTLV-1), interaction of the HTLV-1 integrase with protein phosphatase 2A, and the role of T-cell receptor signaling in HTLV-associated adult T-cell leukemia/lymphoma, as well as development of an envelope mRNA vaccine for HTLV-1. In addition, we are determining the role of immunotherapy in regulation of the tissue microenvironment in Kaposi’s Sarcoma.
